Medical Textiles for Implantation by H. Planck, M. Dauner, M. Renardy

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Medical Textiles for Implantation
by H. Planck, M. Dauner, M. Renardy
Medical Textiles for Implantation

CONTENTS
I. GENERAL ASPECTS
1. General Aspects in the Use of Medical Textiles for Implantation
Planck, H.
2. In vitro Evaluation of the Effects of Macrophages and
synthetic Materials on the Fibroblast Proliferation and Collagen Synthesis
3. Lim, J.O., Chu, C.C., Appel, M.
Contributions to Biocompatibility during Hemodialysis
Seyfert, U.T., Helmling, E., Grothe-Pfautsch, U.,
Albert, F.W., Pindur,G., Wenzel, E.
4. Macroporous Textile and Microporous Nonwoven Vascular
Prostheses: Histological Aspects of Cellular Ingrowth
into the Structure
Jerusalem, C.R., Hess, F.
5. Cytotoxicity Tests in the Biological Evaluation of
Medical Devices 6.
7. Muller-Lierheim, W.
Fact Database Mediplast. Polymers in Medicine
Planck, H., Umutyan, G., Konle, S., Kunberger, A.
The Central Register for Side Effects of Biomaterials
Seyfert, U.T., Bohnert, G., Pindur, G., Bambauer, R.,
Jutzler, G., Kiesewetter, H., Wenzel, E
II. LIGAMENTS AND TENDONS
8. Influence of Processing Parameters for Artificial Ligaments
Dauner, M., Planck, H., Syre, I., Dittel, K.-K.
9. Treatment of Ligamentous Instabilities of the Knee-Joint
under the Special Aspect of Prosthetic Ligament Reconstruction
Dittel, K.-K., Dauner, M., Planck, H., syre, I.
10. Histology of Aramide Cords (Kevlar {R}) Used as a
Cruciate Knee Ligament Substitute in the Sheep
Jerusalem, C.R., Dauner, M., Planck, H., Dittel, K.-K.
11. Mechanical Properties of Various Ligament Prostheses
Durselen, L., Claes, L.
III. VASCULAR PROSTHESES
12. Dilatability and stretching Characteristics of Polyester
Arterial Prostheses. Evaluation of the Elastic
Behaviour
Debille, E., Guidoin, R., Charara, J., Torche, D.,
Bernier-Cardou, M., Marceau, D., Boyer, D., Chaput, C.,
Dadgar, L., Cardou, A.
13. Polyurethanes and Their cytocompatibility for Cell
seeding
Gerlach, J., Schauwecker, H.H., Planck, H.
14. Cellular and Cytoskeletal Response of Vascular Cells
to Mechanical Stimulation
Dartsch, P.C., Betz, E.
15. Perigraft Reaction of Vascular Prosthetic Grafts and
Therapeutic Management
pallua, C., Meinecke, H.J., Hepp, W.
IV. SUTURES
16. The Historical Development of sutures comparing the
Manufacturing Process, Handling Characteristics and
Biocompatibility
Kniepkamp, H.
17. Test Methods for surgical Sutures
Planck, H., Weber, 0., Elser, C., Renardy, M., Mayr, K.,
Milwich, M.
18. The Effect of Bacteria on the Degradation of Absorbable
Sutures
Elser, C., Renardy, M., Planck, H.
V. BIOARTIFICIAL ORGANS
19. Bioartificial Endocrine Pancreas. Prerequisites and
Current Status
Federlin, K., Zekorn, T.
20. Improvement of Insulin Diffusion by Protein coating
of Membranes for Use in a Bioartificial Pancreas
Zekorn, T., siebers, U., Bretzel, R.G., Renardy, M.,
Planck, H., Federlin, K.
21. Polymeric Membranes for Use in a Bioartificial Diffusion
Pancreas: Insulin Diffusion in vitro
Renardy, M., Zschocke, P., Planck, H., Trauter, J.,
Zekorn, T., Siebers, U., Federlin, K.
22. Morphological and Functional Studies on Implanted
Diffusion Membranes
Siebers, U., Zekorn, T., Bretzel, R.G., Sturm, R.,
Planck, H., Renardy, M., Trauter, J., Zschocke, P.,
Federlin, K.
23. First Experiences on Epithelialisation of an Expanded
PTFE Tracheal Prosthesis
Gerhardt, H.J., Kaschke, 0., Wenzel, M., B6hm, F.,
Haake, K.
24. Proliferation and Differentiation of Human Ciliated
Epithelia on PTFE-Prostheses
B6hm, F., Wenzel, M., Gerhardt, H.J.
VI. ARTIFICIAL SKIN AND PATCHES
25. Controlled Microporosity: A Key Design Principle for Artificial Skin
Hinrichs, W.L.J., Kuit, J., Feijen, J., Lommen,
E.J.C.M.P., Wildevuur, Ch.R.H.
26. A New Kind of Collagen Membrane to be Used as Long Term Skin Substitute
Hafemann, B., Sauren, B., Hettich, R.
27. The Gore-Tex Surgical Membrane for Temporary Skin
Closure after Complicated Cardiac operations
Mestres, C.A., Pomar, J.L., Barriuso, C., Ninot, S., Mulet, J.
28. Pathological Analysis of the Explanted Gore-Tex surgical
Membrane after Surgical Implantation
Mestres, C.A., Pomar, J.L.
29. Bioabsorbable Non-Woven Fabric for Surgery
Nakamura, T., Shimizu, Y., Watanabe, S., Shiraki, K.,
Hyon, S.-H., Suzuki, M., Shimamoto, T., Ikada, Y.
30. Water Vapor and Oxygen Permeabilities of Polyetherurethanes
Karakelle, M., Taller, R.A.
ROUNDTABLE DISCUSSION AT THE END OF THE CONFERENCE 343
KEYWORDS 351
AUTHOR INDEX 353

PREFACE
Triennial the Division of Biomedical Engineering of the Institute of Textile Technology and Chemical Engineering, Denkendorf, is organizing conferences on specific topics in the field of polymeric materials for use in the biomedical areas. The aim is to bring together scientists from allover the world working on this specific topic, to present the newest state of the art and to discuss their problems in a more concentrated atmosphere and at last to create and intensivate their cooperation.

Following two conferences on "Polyurethanes in Biomedical Engineering" (1983 and 1986), the Institute of Textile Technology and Chemical Engineering set a theme, which is very closely related to its own task: "Medical Textiles for Implantation".

As technical materials, textiles can be classified in two fields of application:

- first, textiles used for highly flexible, strong, but only tension load bearing systems, e.g. tows;

- second, textiles manufactured to flat shaped devices to separate two regions more or less semipermeable, e.g. clothing;

- a combination of both are reinforced systems like tubular fabrics e.g.; here pressure load will be transformed to tensile load, the separation may be performed by a coating.

In the biological systems the classification can be used in the same manner:

- Tension load bearing structures are ligaments and tendons, semipermeable separation is realized by cell membranes as well as by cell layers, for example the skin.

- The combination of both of the principles can be found for example in arteries and the trachea.

While collagen builds up the load bearing fibers, bidirectional oriented smooth muscle cells transform pressure in the blood vessels to tensile load. starting with the more basic contributions to the use of textiles and polymers in biomedical applications, these proceedings are continued with load bearing suture materials and ligament prostheses. Vascular and tracheal prostheses combine both functions; the coating may have synthetic or autologous origin. Finally separation by a technical structure is required in bioartificial organs as well as in the artificial skin.

The papers are completed by selected remarks taken from the discussions. The round table discussion is referred, too, to give a more general scope.


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