Pharmacotherapy Principles & Practice, 6th Edition PDF by Marie A Chisholm-Burns, Terry L Schwinghammer, Patrick M Malone, Jill M Kolesar, Kelly C Lee and P Brandon Bookstaver


Pharmacotherapy Principles & Practice, Sixth Edition

By Marie A. Chisholm-Burns, Terry L. Schwinghammer, Patrick M. Malone, Jill M. Kolesar, Kelly C. Lee and P. Brandon Bookstaver

Pharmacotherapy Principles & Practice, Sixth Edition


About the Editors xi

Contributors xv

Reviewers xxv

Student and Resident Reviewers xxix

Preface xxxiii

Introduction xxxv


  1. Geriatrics: Safe Medication Use in Older Adults 3

Jeannie K. Lee, Damian M. Mendoza, and Shaun M. Chatelain

  1. Pediatrics Pharmacotherapy 15

Hanna Phan, Vinita B. Pai, and Milap C. Nahata

  1. Palliative Care Management 27

Kelly R. Kroustos and Marc A. Sweeney

  1. Critical Care Pharmacotherapy 39

Brittany D. Bissell and Brian W. Gilbert

  1. Global Health and Travel Medicine 49

Sonak D. Pastakia, Alyssa P. Gould, Benson N. Njuguna, and Jeffrey W. Hall


SECTION 1 Cardiovascular Disorders 85

  1. Hypertension 85

Augustus Hough, Ya-Feng Wen, Jonathan Taylor Huff, Jeffery L. Kibert II, and Shannon W. Finks

  1. Heart Failure 107

Tien M. H. Ng and Samantha L. Yeung

  1. Stable Ischemic Heart Disease 135

Dejan Landup and Dawn Havrda

  1. Acute Coronary Syndromes 157

Kelly C. Rogers and Sarah A. Spinler

  1. Arrhythmias 185

Robert B. Parker and James C. Coons

  1. Venous Thromboembolism 213

James C. Lee, Bryan Zobeck, and Edith A. Nutescu

  1. Stroke 243

Susan R. Winkler

  1. Dyslipidemia 257

Joel C. Marrs and Matthew D. Kostoff

  1. Circulatory Shock Syndromes 279

Bradley A. Boucher and G. Christopher Wood

SECTION 2 Respiratory Disorders 293

  1. Asthma 293

Lori Wilken and Amanda Eades

  1. Chronic Obstructive Pulmonary Disease 311

Jon P. Wietholter and Tara R. Whetsel

  1. Cystic Fibrosis 325

Kimberly J. Novak

SECTION 3 Gastrointestinal Disorders 337

  1. Gastroesophageal Reflux Disease 337

Jeremy J. Prunty and Leesa M. Prunty

  1. Peptic Ulcer Disease 347

Ashley H. Meredith

  1. Inflammatory Bowel Disease 357

Brian A. Hemstreet

  1. Nausea and Vomiting 373

Sheila Wilhelm and Melissa Lipari

  1. Constipation, Diarrhea, and Irritable Bowel Syndrome 383

Beverly C. Mims

  1. Portal Hypertension and Cirrhosis 401

Laurajo Ryan

  1. Pancreatitis 413

Lara M. Groetzinger

  1. Viral Hepatitis 423

Juliana Chan

SECTION 4 Renal Disorders 439

  1. Acute Kidney Injury 439

Mary K. Stamatakis

  1. Chronic and End-Stage Kidney Disease 453

Kristine S. Schonder and Alicia Lichvar

  1. Fluids and Electrolytes 479

Mark A. Malesker and Lee E. Morrow

  1. Acid–Base Disturbances 493

Lee E. Morrow and Mark A Malesker

SECTION 5 Neurologic Disorders 503

  1. Alzheimer Disease 503

Megan J. Ehret and Kevin W. Chamberlin

  1. Multiple Sclerosis 513

Sarah Rajkovic and Jacquelyn L. Bainbridge

  1. Epilepsy 529

Timothy E. Welty and Edward Faught

  1. Status Epilepticus 547

Eljim P. Tesoro and Gretchen M. Brophy

  1. Parkinson Disease 557

Thomas R. Smith

  1. Pain Management 571

Christine Karabin O’Neil

  1. Headache 585

Laurie W. Fleming, Leigh Ann Ross, and Brendan S. Ross

SECTION 6 Psychiatric Disorders 595

  1. Substance-Related Disorders 595

Chris Paxos and Christian J. Teter

  1. Schizophrenia 611

Deanna L. Kelly, Mary Borovicka, and Heidi J. Wehring

  1. Major Depressive Disorder 633
  2. Michael McGuire and Cherry W. Jackson
  3. Bipolar Disorder 651

Sarah E. Goldsborough, Opal M. Bacon, and Lydia E. Weisser

  1. Anxiety and Trauma-Related Disorders 665

Bridget Bradley

  1. Sleep Disorders 681

Jessa Marie Koch and Azita Alipour

  1. Attention-Deficit/Hyperactivity Disorder 693

Kevin W. Cleveland, Julia Boyle, and Renee F. Robinson

SECTION 7 Endocrinologic Disorders 701

  1. Diabetes Mellitus 701

Julie M. Sease and Elizabeth W. Blake

  1. Thyroid Disorders 731

Michael D. Katz

  1. Adrenal Gland Disorders 749

Christina M. Polomoff, Devra K. Dang, and Judy T. Chen

  1. Pituitary Gland Disorders 765

Christina M. Polomoff, Devra K. Dang, and Judy T. Chen

SECTION 8 Gynecologic and Obstetric Disorders 785

  1. Pregnancy and Lactation: Therapeutic Considerations 785

Rebecca H. Stone

  1. Contraception 803

Julia M. Koehler and Kathleen B. Haynes

  1. Menopause and Menstruation-Related Disorders 817

Nicole E. Cieri-Hutcherson and Kylie N. Barnes

SECTION 9 Urologic Disorders 837

  1. Erectile Dysfunction 837

Cara Liday

  1. Benign Prostatic Hyperplasia 847

Mary Lee and Roohollah Sharifi

  1. Urinary Incontinence and Pediatric Enuresis 863

Sum Lam and Gladys El-Chaar

SECTION 10 Immunologic Disorders 881

  1. Drug Hypersensitivity Reactions 881
  2. Russell May, Dixie D. Griffin, and Kathleen May
  3. Solid Organ Transplantation 891

Steven Gabardi, Miae Kim, and Ali J. Olyaei

  1. Systemic Lupus Erythematosus 915

Cassandra Dolecki, Marisha Okpala, and Jessica Farrell

SECTION 11 Bone and Joint Disorders 937

  1. Osteoporosis 937

Beth Bryles Phillips and Morgan K. Moulton

  1. Rheumatoid Arthritis 951

Susan P. Bruce

  1. Osteoarthritis 967

Christopher R. Piszczatoski, Steven M. Smith, and John Gums

  1. Gout and Hyperuricemia 979

Maria Miller Thurston and Jenny Lin

  1. Musculoskeletal Injuries 991

Jill S. Borchert and Lisa M. Palmisano

SECTION 12 Disorders of the Eyes, Ears, Nose, and Throat 1003

  1. Glaucoma 1003

Daniel O. Clegg, Jr.

  1. Minor Ophthalmic and Otic Disorders 1017

Lauren R. Biehle and Michelle L. Hilaire

  1. Nose, Mouth, and Throat Disorders 1029

Alexandra Hintz, Phu Trinh, and Luke Dearden

  1. Allergic Rhinitis 1049

Hanna Phan and Michael Daines

SECTION 13 Dermatologic Disorders 1065

  1. Acne Vulgaris 1065

Laura A. Perry and Jenna M. Mills

  1. Dermatitis 1075

Lori Ernsthausen and Jenna M. Mills

  1. Psoriasis 1087

Amy K. Kennedy

SECTION 14 Hematologic Disorders 1103

  1. Anemia 1103

Maribel A. Pereiras

  1. Coagulation and Platelet Disorders 1117

Anna Dushenkov and Paiboon Jungsuwadee

  1. Sickle Cell Disease 1137

Tracy M. Hagemann and Teresa V. Lewis

SECTION 15 Diseases of Infectious Origin 1151

  1. Patient Assessment, Antimicrobial Selection, and Stewardship 1151

Angharad Ratliff and Catherine Oliphant

  1. Central Nervous System Infections 1167

April Miller Quidley and P. Brandon Bookstaver

  1. Lower Respiratory Tract Infections 1185

Diane M. Cappelletty

  1. Upper Respiratory Tract Infections 1199

Heather L. Girand

  1. Skin and Skin Structure Infections 1217

Jaime R. Hornecker and Lauren R. Biehle

  1. Osteomyelitis 1229

Jessica E. Burchette and David B. Cluck

  1. Infective Endocarditis 1237

Ronda L. Akins

  1. Tuberculosis 1255

Rocsanna Namdar and Charles Peloquin

  1. Gastrointestinal Infections 1267

Megan M. Seddon and Jamie J. Kisgen

  1. Intra-Abdominal Infections 1279

Joseph E. Mazur and Melanie Smith Condeni

  1. Urinary Tract Infections and Prostatitis 1289

Spencer H. Durham

  1. Sexually Transmitted Infections 1299

Marlon S. Honeywell and Evans Branch, III

  1. Sepsis and Septic Shock 1321

Trisha N. Branan, Susan E. Smith, and Christopher M. Bland

  1. Superficial Fungal Infections 1333

Kathryn A. Fuller and Lauren S. Schlesselman

  1. Invasive Fungal Disease 1345

Jeffrey M. Rybak

  1. Human Immunodeficiency Virus Infection 1363

Mary F. Banoub, Jennifer L. Bailey, and Fidelia Bernice

SECTION 16 Oncologic Disorders 1389

  1. Cancer Principles and Therapeutics 1389

Lisa M. Holle

  1. Breast Cancer 1421

Gerald M. Higa

  1. Lung Cancer 1435

Ninh M. La-Beck and Christopher Selby

  1. Colorectal Cancer 1455

Emily B. Borders and Allison Baxley

  1. Prostate Cancer 1471

Amber B. Cipriani and Daniel J. Crona

  1. Melanoma 1487

Chung-Shien Lee

  1. Ovarian Cancer 1503

Judith A. Smith

  1. Lymphomas 1517

Keith A. Hecht and Susanne Liewer

  1. Acute Leukemias 1529

Nancy H. Heideman and Dulcinea Quintana

  1. Chronic Leukemias and Multiple Myeloma 1545

Amy M. Pick and Jared E. Matya

  1. Hematopoietic Stem-Cell Transplantation 1561

Gianni Scappaticci and David G. Frame

  1. Supportive Care in Oncology 1581

Alexandre Chan and Lee Nguyen

SECTION 17 Nutrition and Nutritional Disorders 1611

  1. Parenteral Nutrition 1611

Melissa R. Pleva and Michael D. Kraft

  1. Enteral Nutrition 1631

Sarah J. Miller

  1. Overweight and Obesity 1645

April Smith

Appendices 1657

Appendix A: Prescription Writing Principles 1657

Appendix B: Conversion Factors and Anthropometrics 1661

Appendix C: Common Medical Abbreviations 1665

Appendix D: Glossary 1671

Index 1691

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